Botulinum toxin A as treatment for drooling saliva in PD
Identifieur interne : 003593 ( Main/Exploration ); précédent : 003592; suivant : 003594Botulinum toxin A as treatment for drooling saliva in PD
Auteurs : P. K. Pal [Canada] ; D. B. Calne [Canada] ; S. Calne [Canada] ; J. K. C. Tsui [Canada]Source :
- Neurology [ 0028-3878 ] ; 2000.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Personne âgée.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Bontoxilysin, Botulinum Toxins, Type A (therapeutic use), Botulism, Complication, Elderly, Female, Humans, Injections, Local administration, Male, Middle Aged, Parkinson Disease (complications), Parkinson disease, Parotid Gland (drug effects), Parotid Gland (secretion), Parotid gland, Saliva (drug effects), Saliva (secretion), Sialorrhea, Sialorrhea (drug therapy), Sialorrhea (etiology), Toxin, Treatment, Treatment Outcome.
- MESH :
- chemical , therapeutic use : Botulinum Toxins, Type A.
- complications : Parkinson Disease.
- drug effects : Parotid Gland, Saliva.
- drug therapy : Sialorrhea.
- etiology : Sialorrhea.
- secretion : Parotid Gland, Saliva.
- Aged, Aged, 80 and over, Female, Humans, Injections, Male, Middle Aged, Treatment Outcome.
Abstract
Article abstract-The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease.
Affiliations:
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Le document en format XML
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<term>Aged, 80 and over</term>
<term>Bontoxilysin</term>
<term>Botulinum Toxins, Type A (therapeutic use)</term>
<term>Botulism</term>
<term>Complication</term>
<term>Elderly</term>
<term>Female</term>
<term>Humans</term>
<term>Injections</term>
<term>Local administration</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson disease</term>
<term>Parotid Gland (drug effects)</term>
<term>Parotid Gland (secretion)</term>
<term>Parotid gland</term>
<term>Saliva (drug effects)</term>
<term>Saliva (secretion)</term>
<term>Sialorrhea</term>
<term>Sialorrhea (drug therapy)</term>
<term>Sialorrhea (etiology)</term>
<term>Toxin</term>
<term>Treatment</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Botulinum Toxins, Type A</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Parotid Gland</term>
<term>Saliva</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Sialorrhea</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Sialorrhea</term>
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<term>Saliva</term>
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<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Injections</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Treatment Outcome</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term>
<term>Sialorrhée</term>
<term>Botulisme</term>
<term>Toxine</term>
<term>Bontoxilysin</term>
<term>Voie locale</term>
<term>Glande parotide</term>
<term>Traitement</term>
<term>Complication</term>
<term>Personne âgée</term>
<term>Bave</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Personne âgée</term>
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<front><div type="abstract" xml:lang="en">Article abstract-The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease.</div>
</front>
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<tree><country name="Canada"><noRegion><name sortKey="Pal, P K" sort="Pal, P K" uniqKey="Pal P" first="P. K." last="Pal">P. K. Pal</name>
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<name sortKey="Calne, D B" sort="Calne, D B" uniqKey="Calne D" first="D. B." last="Calne">D. B. Calne</name>
<name sortKey="Calne, S" sort="Calne, S" uniqKey="Calne S" first="S." last="Calne">S. Calne</name>
<name sortKey="Tsui, J K C" sort="Tsui, J K C" uniqKey="Tsui J" first="J. K. C." last="Tsui">J. K. C. Tsui</name>
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